Excess Alcohol use may Increase risk of cancer
A new research has suggested that too much consumption of alcohol may raise the risk of cancer and even cause premature aging. This is because of shortening of telomeres, an area of DNA successions at the end of a chromosome, which is vital for the genetic stableness of cells. As people grow old, telomere length reduces progressively. Too much use of alcohol has been linked to oxidative strain and swelling, two mechanisms, which speed up telomere shortening. Since telomere shortening is believed to raise the risk of cancer, the scientists speculated that those with shorter telomeres owing to heavy alcohol intake would have an increased cancer risk. Andrea Baccarelli who heads the Centre of Molecular and Genetic Epidemiology, Ca’ Granda Hospital Foundation, University of Milan, Italy, “Heavy alcohol users tend to look haggard, and it is commonly thought that heavy drinking leads to premature aging and earlier onset of diseases of aging. In particular, heavy alcohol drinking has been associated with cancer at multiple sites.” “All the cells in our body have a biological clock in telomeres,” Baccarelli added. The study scientists measured serum DNA among 59 partakers who ill-used alcohol and 197 partakers with variable alcohol ingestion habits. The two groups were similar in age and other components, which might have an effect on telomere length, like diet, workout, work-related tension and environmental exposures. The outcomes of the study showed that telomere length was noticeably shortened in those who had heavy amounts of alcohol. The study outcomes were released at the American Association for Cancer Research’s 101st annual meeting. If you have ever seen a person who has had too much to drink, you know that alcohol is a drug that has widespread effects on the body, and the effects vary from person to person. People who drink might be the “life of the party” or they might become sad and droopy. Their speech may slur and they may have trouble walking. It all depends on the amount of alcohol consumed, a person’s history with alcohol and a person’s personality. Even though you have seen the physical and behavioral changes, you might wonder exactly how alcohol works on the body to produce those effects. What is alcohol? How does the body process it? How does the chemistry of alcohol work on the chemistry of the brain? In this article, we will examine all of the ways in which alcohol affects the human body. 
The Effects of Alcohol
If you have seen someone who has had too much to drink, you’ve probably noticed definite changes in that person’s performance and behavior. The body responds to alcohol in stages, which correspond to an increase in BAC
1. Euphoria (BAC = 0.03 to 0.12 percent)
* They become more self-confident or daring.
* Their attention span shortens.
* They may look flushed.
* Their judgement is not as good — they may say the first thought that comes to mind, rather than an appropriate comment for the given situation.
* They have trouble with fine movements, such as writing or signing their name.
2. Excitement (BAC = 0.09 to 0.25 percent)
* They become sleepy.
* They have trouble understanding or remembering things (even recent events).
* They do not react to situations as quickly (if they spill a drink they may just stare at it).
* Their body movements are uncoordinated.
* They begin to lose their balance easily.
* Their vision becomes blurry.
* They may have trouble sensing things (hearing, tasting, feeling, etc.).
3. Confusion (BAC = 0.18 to 0.30 percent)
* They are confused — might not know where they are or what they are doing.
* They are dizzy and may stagger.
* They may be highly emotional — aggressive, withdrawn or overly affectionate.
* They cannot see clearly.
* They are sleepy.
* They have slurred speech.
* They have uncoordinated movements (trouble catching an object thrown to them).
* They may not feel pain as readily as a sober person.
4. Stupor (BAC = 0.25 to 0.4 percent)
* They can barely move at all.
* They cannot respond to stimuli.
* They cannot stand or walk.
* They may vomit.
* They may lapse in and out of consciousness.
5. Coma (BAC = 0.35 to 0.50 percent)
* They are unconscious.
* Their reflexes are depressed (i.e. their pupils do not respond appropriately to changes in light).
* They feel cool (lower-than-normal body temperature).
* Their breathing is slower and more shallow.
* Their heart rate may slow.
* They may die.